Every day in the U.S., more than 40 people die after overdosing on prescription painkillers. Deaths from a more notorious form of opiates — heroin — increased five-fold between 2001 and 2013. Addressing this problem — one that’s often described as a public health crisis — requires action on many fronts, from preventing abuse in the first place to getting those addicted into treatment. But when it comes to overdoses, there’s one answer we know works: naloxone.